Urinary tract infections (UTIs) are a huge issue for around eight million people yearly in the USA. These infections are more prevalent in woman. The treatment most often recommended by conventional medicine is antibiotics which can be used as an acute dosage and for recurrent infections, low doses of antibiotics may be prescribed daily for six months or more. This increases the risk of developing antibiotic-resistant strains besides being detrimental to the healthy colonic bacteria.
D-mannose can actually be derived from berries, peaches, apples, and some other plants and is the active ingredient in cranberry juice for UTI prevention. Although cranberry juice is often a suggested remedy it is high in fructose and sugar. This high sugar concentration has negative effects on the gut bacteria. Moreover pure D-mannose is about 10-50 times stronger than cranberry, non-toxic and completely safe, with NO adverse effects.
When E. coli moves into your urinary tract and multiplies, the following symptoms may be experienced – the common UTI symptoms.
D-mannose does not convert to glycogen or get stored in your liver. Only very small amounts of D-mannose are metabolized, so it doesn't interfere with blood sugar regulation. Every cell in the body is designed to use D-Mannose but the absorption rate is extremely slow. Most of the D-mannose is filtered through your kidneys and routed to your bladder, then quickly excreted in your urine, making it ideal for people with diabetes or anyone who is not interested in drinking sugary fruit juice.
D-Mannose is a natural healthy alternative which is effective 85-90% of the time. It can be used for treating acute UTIs, for prophylaxis in women prone to recurrent infections or for the prevention of post-intercourse UTIs and it's safe for both adults and children. D-mannose powder has been shown to significantly reduce the risk of recurrent UTI in clinical trials.
Most UTIs are caused by Escherichia coli (E. coli), which is normally found in your intestinal tract. Problems arise when this ordinary bacterium is present in high numbers in the urinary tract.
The cell walls of each E. coli are covered with tiny finger like projections called fimbria allowing them to "stick" to the inner walls of your bladder and even work their way upward to your ureter and kidneys. These sticky, finger like projections consist of an amino acid-sugar complex, a glycoprotein called lectin. Lectin on the bacteria's fimbria binds to mannose, which is produced by our urinary epithelial cell walls cells and covers the internal lining of our urinary organs. This mannose allows the bacteria to adhere to our epithelial tissue in our urinary system. But as Dr. Wright explains, when you take D-mannose it sticks to the E. coli better than the E coli sticks to the mannose in our epithelial tissue allowing the E. coli to be enveloped and effectively "rinsed" out via urination:
The following dosages have been suggested.
Acute treatment of UTIs: 5ml (about 2 grams) for adults, 2.5 – 5ml for children, dissolved in a glass of water and repeated every two to three hours. Continue for two to three days after symptoms have disappeared.
Prevention of recurring infections; start with the dosages listed above for treatment, then gradually reduce the dose, to the lowest dosage for efficacy.
Prevention of post-intercourse UTI’s 12.5ml one hour prior to intercourse and another tablespoon immediately afterward.